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Dogzymes Estrus-Mate Supplement
Nature's Farmacy

Dogzymes Estrus-Mate Supplement

Verified Aug 28, 2026

Dog · Supplement Adult All Breed Sizes

This is a botanical powder supplement for adult breeding female dogs, made with lecithin, red raspberry leaf, maca, selenium yeast, and kelp. It’s intended to be used alongside a complete diet to support normal hormonal cycles and general reproductive wellness around breeding.

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Over-the-counter No recalls

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Official product page
KibbleLab Score
8.0 out of 10

Strong Choice

This supplement is designed specifically for intact adult female dogs being prepared for breeding. It combines several plant-based ingredients and trace nutrients that are commonly used in reproductive-support formulas. It should always be used in addition to a complete and balanced diet and under guidance from your veterinarian, especially for breeding plans.

Actives and dosage disclosure 6.0
Ingredient composition 8.0
Health considerations 10.0

Computed from 3 of 3 applicable checks. Missing data is skipped, never counted against a food.

The KibbleLab Score (1–10) is assessed from publicly available product data. Our evaluation is science-based, not marketing-based.

Nutritional profile Protein, fat, fiber on a dry-matter basis, for the stated life stage and format
Adequacy substantiation Complete and balanced substantiation; feeding trials valued higher
Ingredient composition Screened for unnamed sources, artificial additives, and label protein inflation. Not a quality ranking.
Health considerations Pulse-heavy grain-free (DCM) pattern and recall history
Verified manufacturer evidence A small bonus when we can verify evidence addressing WSAVA selection criteria
9.0 - 10 Top Pick
8.0 - 8.9 Strong Choice
7.0 - 7.9 Solid Option
6.0 - 6.9 Worth a Conversation
Below 6.0 Review Carefully

KibbleLab may earn an affiliate commission when you buy through a link. No one can pay for a higher score, or to change what we recommend for your pet.


At a Glance

Suitable For
Adult All Breed Sizes
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We'll check every ingredient against your pet's sensitivities and avoidance list.

Nutritional Perspective

KibbleLab Review

Strengths

  • Simple ingredient list centered on botanicals like red raspberry leaf and maca, which many breeders look for in cycle-support supplements.
  • Includes selenium yeast and kelp, which can provide trace minerals and iodine alongside a normal diet.
  • Powder form makes it relatively easy to mix into food for most dogs.

Considerations

  • This is a supplement only and does not provide complete nutrition, so it must be fed with a balanced dog food.
  • Any product aimed at hormone or reproductive support should be discussed with your vet before use, especially in dogs with existing health issues.
  • Herbal blends can cause stomach upset or interact with medications in some dogs, so start slowly and watch for any changes.
Scored using the rubric of an NAVC Certified Pet Nutrition Coach (PNCC). This is informational, not veterinary advice.

Full Ingredient List

Lecithin Powder, Red Raspberry Leaf Powder, Maca Powder, Selenium Yeast, Wild Harvested Kelp

Ingredients and analysis reflect manufacturer data at the time of our last update and can change without notice. Always check the actual product packaging before feeding.

Ingredient filtering helps identify compatible options but is not a substitute for a veterinary elimination diet.

Top 5 Ingredients Explained

01
Lecithin
Lecithin is commonly used in pet foods as an emulsifier and texture stabilizer—typically derived from soy, sunflower, or egg—and supplies phospholipids (such as phosphatidylcholine) that help disperse fats and maintain product consistency. In small amounts it contributes choline and supports fat digestion and cell membrane health, but it is not a primary nutrient source; soy-derived lecithin may be a consideration for pets with soy sensitivities and very high intakes can occasionally cause mild gastrointestinal upset.
02
Red Raspberry Leaf
Red raspberry leaf is used in pet foods and supplements as a botanical ingredient for its mild astringent and antioxidant properties and is included primarily for phytochemicals (flavonoids, tannins, trace vitamins and minerals) or flavor rather than as a primary protein or fiber source. It may offer antioxidant support and has traditional uses related to female reproductive health, but evidence in dogs and cats is limited, so it should be used in small amounts with caution in pregnant animals or pets on medications and only under veterinary guidance.
03
Maca
Maca is a powdered root supplement from the Andean plant Lepidium meyenii that is used in pet foods and treats as a botanical additive and mild source of carbohydrates, fiber and trace vitamins and minerals rather than a primary macronutrient. It is sometimes promoted for energy or hormonal support in dogs and cats, but evidence in pets is limited and it can cause gastrointestinal upset or potentially affect hormone‑sensitive conditions or interact with medications, so veterinary guidance is recommended before use.
04
Selenium Yeast
Selenium yeast is included in pet foods as a highly bioavailable, organic source of the essential trace mineral selenium, which supports antioxidant enzyme systems and normal thyroid and immune function in dogs and cats. It can be more readily absorbed than inorganic selenium, but because selenium has a narrow safe range, formulas should follow established nutritional guidelines (e.g., AAFCO/FEDIAF) to avoid deficiency or toxic excess, and owners should be cautious about additional selenium-containing supplements.
05
Kelp
Kelp is a dried seaweed ingredient used in dog and cat foods primarily for trace minerals (notably iodine), vitamins, fiber, and natural flavor rather than as a significant protein or energy source. It can support skin, coat and general micronutrient intake, but iodine levels are highly variable and excessive iodine or contaminants from poorly sourced kelp can affect thyroid function or introduce heavy metals, so pets with thyroid disease should have intake discussed with their veterinarian and products should come from reputable suppliers.


Product Details & Brand

Product Specs

Lifestage Adult
Breed size All Breed Sizes
Texture Powder
Food type Supplement

Brand

Nature's Farmacy is the flagship brand offering animal health supplements, probiotics, digestive enzymes, and nutritional support products. It focuses on holistic, natural wellness solutions for pets and performance animals, targeting consumers seeking science-based yet natural options for animal health.

Price tier $$$

Manufacturer

Company name Nature's Farmacy Inc.
Founded 1984
Headquarters Jasper, Georgia, USA
Manufacturing type In House
Manufacturing country United States
Manufacturing region Georgia
Manufacturing oversight

Products are manufactured in the USA under strict in-house quality control procedures. The company oversees its production to ensure consistency, purity, and efficacy of supplements, adhering to standard GMP (Good Manufacturing Practices) for animal supplements.

Manufacturing details are compiled from public sources and not independently verified; they may not reflect contract manufacturing or co-packing.

Recall History

No recalls on record

No recall is listed for Nature's Farmacy Dogzymes Estrus-Mate Supplement.

Source: FDA animal food recall listings back to January 2019 · Checked daily, last on Aug 31, 2026

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KibbleLab food report
GREAT BOWL.
8.0 /10 Grade A
Dogzymes Estrus-Mate Supplement
Nature's Farmacy · kibblelab.com

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Frequently Asked Questions

Has Nature's Farmacy ever been recalled?

We have no recalls on record for Nature's Farmacy. We track the FDA's animal food recall listings back to January 2019 and publish every pet food recall automatically. A filing that isn't pet food may not appear here.

How does KibbleLab rate foods?

Our scores are based on ingredient composition, nutritional profile, AAFCO compliance, and health considerations. We don't penalize by-products, grains, or synthetic preservatives. Brands cannot pay for higher scores.

Is KibbleLab a substitute for veterinary advice?

No. KibbleLab provides data-driven food analysis, not medical advice. Always consult your veterinarian before making dietary changes, especially for pets with health conditions.

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KibbleLab provides informational content only. This is not veterinary advice. Always consult a qualified veterinarian before changing your pet's diet.

KibbleLab may earn affiliate commissions through product links. No one can pay for a higher score, or to change what we recommend for your pet.

Product data sourced from manufacturer websites, AAFCO statements, and FDA recall listings. Last verified dates reflect our most recent data check. We track the FDA's animal food recall listings back to January 2019 and publish every pet food recall automatically. A filing that isn't pet food may not appear here.