ProDen PlaqueOff Large & Giant Breed Dog Soft Chew Supplement
Verified Jun 8, 2026
A dental-support soft chew supplement for large and giant breed dogs, featuring ProDen PlaqueOff organic Scandinavian kelp as the key active ingredient. The kelp, along with yeast and carbohydrate carriers, is designed to help support oral hygiene and fresher breath when used daily. This is intended as a supplement alongside a complete diet, not as a primary food source.
This is a well-formulated dental supplement for large and giant breed dogs, built around a clinically studied kelp ingredient to help support oral health and breath quality. The ingredient list is straightforward, with the active kelp clearly identified and supported by common soft chew carriers and natural preservatives. It can be a reasonable option for owners looking to add dental support on top of regular toothbrushing and professional cleanings.
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At a Glance
KibbleLab Review
Strengths
- Uses a defined active ingredient (ProDen PlaqueOff organic Scandinavian kelp), which has some clinical research supporting its role in reducing plaque and tartar.
- Formulated as a soft chew, which tends to be easy to give to large and giant breed dogs and simple to dose based on body weight.
- Ingredient list is relatively simple, using common palatability and texture agents and natural preservatives like mixed tocopherols and rosemary extract.
- Specifically dosed for larger dogs (over 50 lb), which helps reduce the risk of under-dosing in big breeds compared with “one-size-fits-all” chews.
Considerations
- This is a supplement only and does not provide complete and balanced nutrition, so it must be used alongside a regular dog food diet.
- Contains brewers dried yeast, which is safe for most dogs but may not suit those with a known sensitivity to yeast.
- As with any kelp-based product, iodine content may be a consideration for dogs with certain thyroid conditions; if your dog has thyroid disease, it’s best to discuss this with your veterinarian before use.
- Dental supplements work best as part of a broader dental care plan, so relying on this alone without brushing or veterinary cleanings may not give optimal oral health results.
Full Ingredient List
Ingredients and analysis reflect manufacturer data at the time of our last update and can change without notice. Always check the actual product packaging before feeding.
Ingredient filtering helps identify compatible options but is not a substitute for a veterinary elimination diet.
Top 5 Ingredients Explained
01
Kelp
Kelp is a dried seaweed ingredient used in dog and cat foods primarily for trace minerals (notably iodine), vitamins, fiber, and natural flavor rather than as a significant protein or energy source. It can support skin, coat and general micronutrient intake, but iodine levels are highly variable and excessive iodine or contaminants from poorly sourced kelp can affect thyroid function or introduce heavy metals, so pets with thyroid disease should have intake discussed with their veterinarian and products should come from reputable suppliers.
02
Brewer's Yeast
Brewer's yeast (deactivated Saccharomyces cerevisiae) is commonly used in dog and cat foods as a flavor enhancer and supplemental source of protein, B‑complex vitamins, trace minerals and immunomodulating components such as beta‑glucans. It can support skin, coat and general nutritional status, but may cause gastrointestinal upset or allergic reactions in yeast‑sensitive pets, is not a live probiotic, and should be used cautiously in animals prone to purine‑related issues or those receiving antifungal medications.
03
Canola Oil
Canola oil is used in pet foods as a concentrated fat source and palatability enhancer that supplies energy and essential fatty acids—mainly omega‑6 (linoleic acid) and some omega‑3 (ALA)—and aids absorption of fat‑soluble vitamins. It can support skin and coat condition when balanced with animal fats or supplemental omega‑3s, but is calorie‑dense so must be portioned to avoid weight gain, does not provide species‑specific fats such as arachidonic acid for cats, and must be kept fresh to prevent oxidation.
04
Potato Product
Potato products (such as flakes, meals or starch) are commonly used in pet foods as a digestible carbohydrate, binder and texture enhancer that contributes energy and palatability. They provide readily available calories and some minerals (e.g., potassium) and can serve as a gluten‑free carbohydrate alternative, but are high in starch and glycemic load—which may promote weight gain or affect blood glucose control in diabetic pets—and processing can reduce vitamin content; cats still require primarily animal protein despite tolerating some starch.
05
Glycerol
Glycerol (glycerin) is used in pet foods primarily as a humectant and sweetening agent to retain moisture, improve texture and palatability, and serve as a solvent or carrier in wet foods, treats, and liquid supplements. It provides a modest source of metabolizable energy for dogs and cats, but in large amounts can cause gastrointestinal upset and may affect blood glucose, so products intended for diabetic pets or sensitive animals should be used with caution.
Product Details & Brand
Product Specs
Brand
NaturVet is a leading brand of pet supplements offering a wide range of products for dogs, cats, and horses, focusing on natural health support including joint, digestive, allergy, and behavioral care. The brand targets pet owners seeking holistic, natural, and vet-formulated wellness solutions.
Visit NaturVetManufacturer
NaturVet manufactures products in-house at its Temecula, California facility that is compliant with current Good Manufacturing Practices (cGMP). The company maintains NASC (National Animal Supplement Council) certification, ensuring standardized manufacturing, ingredient safety, and product quality.
Manufacturing details are compiled from public sources and not independently verified; they may not reflect contract manufacturing or co-packing.
Recall History
NaturVet ProDen PlaqueOff Large & Giant Breed Dog Soft Chew Supplement has no recalls since 2014.
Source: FDA Pet Food Recall Database · Monitored daily
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Frequently Asked Questions
Has NaturVet ever been recalled?
We have no recalls on record for NaturVet. We monitor the FDA Pet Food Recall Database daily.
How does KibbleLab rate foods?
Our scores are based on ingredient composition, nutritional profile, AAFCO compliance, and health considerations. We don't penalize by-products, grains, or synthetic preservatives. Brands cannot pay for higher scores.
Is KibbleLab a substitute for veterinary advice?
No. KibbleLab provides data-driven food analysis, not medical advice. Always consult your veterinarian before making dietary changes, especially for pets with health conditions.
KibbleLab provides informational content only. This is not veterinary advice. Always consult a qualified veterinarian before changing your pet's diet.
KibbleLab may earn affiliate commissions through product links. No one can pay for a higher score, or to change what we recommend for your pet.
Product data sourced from manufacturer websites, AAFCO statements, and FDA recall database. Last verified dates reflect our most recent data check.